Academics
Acute Creatine Monohydrate Ingestion and Cognitive Performance …
Acute Creatine Monohydrate Ingestion and Cognitive Performance: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study
LU IRB#: IRB-25-23
PI: Chad Kerksick, PhD
Description of Study
The aim of the research study is to examine the acute effects of a single and 3 days of 30-gram doses of creatine monohydrate on cognitive performance measures in healthy adults.
Location
(Fieldhouse 126)
209 S Kingshighway St
Saint Charles, MO 63301
Number of Visits
6 (5 visits to the lab)
Time Commitment
Visits 1-5: 45-60 minutes
Visit 6: 10 minutes
Compensation
$25
Points of Contact
Wyatt McLaughlin
[email protected]
Research Sample Needed
- 50-60 healthy men and women
Inclusion Criteria
- Between 18 and 50 years old.
- In good general health with no unmanaged chronic medical conditions (e.g., hypertension, cardiovascular disease, or neurological disorders).
- No creatine or cognitive-enhancing supplements (e.g., nootropics) within the past 30 days.
- Not currently taking medications that impact cognitive function, sleep, or physiological measures (e.g., sedative, stimulants, antidepressants).
- Must be available to attend all testing visits over 4 consecutive days.
- Must agree to maintain their usual sleep and physical activity routines throughout the study.
- Able to consume the supplement at home (or outside the lab) and arrive at the lab within 150-170 minutes post-ingestion.
- Must report regular sleep patterns (e.g., 6-9 hours per night).
- No history of shift work or frequent travel across time zones within the past 14 days.
Exclusion Criteria
- Diagnosed with or receiving treatment for cardiovascular disease, neurological disorders, or psychiatric conditions.
- Diagnosed with sleep disorders (e.g., insomnia, sleep apnea).
- Pregnant, breastfeeding, or planning to become pregnant during the study period.
- Currently using medications known to affect cognitive function, sleep, or physiological outcomes (e.g., sedatives, stimulants, antidepressants).
- Taken nootropics or other cognitive-enhancing supplements (e.g., modafinil, racetams) within the past 30 days
- Inability to maintain consistent daily routines during the study period (frequent time zone changes, shift work).
- Unwilling or unable to attend all study visits or complete required assessments.
- Non-compliance with the supplementation or data collection protocols.
Are You Eligible?
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Information provided here reflects current IRB approval for this research. However, this information may be subject to change and updated accordingly.